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WebJul 19, 2012 · RANKL expression in sciatic nerves of EAN rat. Rat EAN model has been established and a time course of neurological scores of our EAN library has been published previously [].For this EAN tissue library, the first neurological sign (reduced tonus of tail) was seen at day 12 (1.3 ± 0.8), and maximal severity of neurological signs appeared at 15 … WebOct 6, 2016 · Evidence supports that the various IVIg effects are mediated by its Fc portion as Fc fragment preparations were sufficient to ameliorate rat EAN [10, 11]. Effects of IVIg on the expression of the anti … WebJan 15, 2015 · The EAN rat model, which is the most popular animal model for GBS, is induced by immunization with peripheral myelin homogenates or with peripheral myelin proteins such as the P2(57-81) peptide ... did america buy california